The Mass Spectrometry Laboratory (MSLab) is a consortium of scientists, mainly chemists and biologists, which have developed a unique expertise in Mass Spectrometry and Optical Spectroscopy. Together, MSLab scientists are working on several main topics using and developing mass spectrometry-based methods. The research activities are distributed across 5 main topics: MSLab-Analytics, MSLab-Biology, MSLab-Fun, MSLab-Imaging and MSLab-Omics. Strong interactions between the MSLab experts and OBiAChem group (led by Prof. J-F Focant) or other specialists enable the development of original and innovative chemical methods based mainly on Mass Spectrometry and adapted to the actual and future analytical challenges in the fields of medicine, biology, environment, material sciences, or physical chemistry. The MSLab is also supporting Analytical Platforms for proteomics (Giga proteomics), MS-Quanta and food safety analyses (CART). The MSLab is part of the MolSys Research Unit gathering other experts of various field of sciences.